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Niumee Health Lab TestsMethylmalonic Acid Urine MMA 4M1492
€263.00 Incl. VAT
Methylmalonic Acid Urine MMA 4M1492
Urine MMA testing is vital for detecting mild vitamin B12 deficiency, aiding in early intervention and symptom management.
**Please note: **This test is available in Ireland; however, due to the time-sensitive nature of the sample, it must be shipped directly to the laboratory in Germany. A shipping fee of €60 applies.
An invoice will be issued to the practitioner at the point of purchase. If shipping has already been paid, that amount will be deducted from the final shipping cost.
Tested Biomarkers
- Creatinine
- Methylmalonic Acid (MMA)
Methodology
Methylmalonic Acid Urine (MMA) is analysed by chromatography-mass spectrometry (GC-MS) which is a powerful analytical technique used to separate, identify, and quantify complex mixtures of substances. It combines two methods: gas chromatography (GC) and mass spectrometry (MS). In gas chromatography, the sample is vaporized and injected into a heated column where different compounds separate based on their affinity for the column material and their boiling points. As each compound elutes from the column, it enters the mass spectrometer. In mass spectrometry, compounds are ionized and fragmented into charged particles. The resulting ions are then sorted based on their mass-to-charge ratio (m/z), producing a mass spectrum that serves as a fingerprint for each compound. By analyzing the retention times in GC and the mass spectra in MS, GC-MS can identify and quantify individual components within a mixture with high sensitivity and specificity.
When should you conider this test?
Considering the Urine MMA test is vital for mild vitamin B12 deficiency detection, aiding early intervention and symptom management, and offering insights into metabolic health.
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